Male reproductive toxicity of zearalenone—meta-analysis with mechanism review
نویسندگان
چکیده
منابع مشابه
Integrated proteomics and metabolomics analysis of rat testis: Mechanism of arsenic-induced male reproductive toxicity
Arsenic is a widespread metalloid in environment, whose exposure has been associated with a broad spectrum of toxic effects. However, a global view of arsenic-induced male reproductive toxicity is still lack, and the underlying mechanisms remain largely unclear. Our results revealed that arsenic exposure decreased testosterone level and reduced sperm quality in rats. By conducting an integrated...
متن کاملP-43: Reproductive Toxicity of Low Metal Exposureon Male
Background: Recent evidence has indicated a deterioration in reproductive health of men in many countries over the past few decades, particularly a decrease in semen quality and an increase in prevalence of prostate cancer. The human male has a relatively low fertility potential as compared to other mammals. Thus, the human male may be at greater risk from reproductive toxicants. For example, t...
متن کاملA review of acrylamide toxicity and its mechanism
Acrylamide (AA) is an important industrial chemical agent that is mainly used in the production of polymers and copolymers. Recently it has been attention because of its production in the diet at high-temperature (>120 ºC) processes such as cooking, frying, toasting, roasting or baking of high carbohydrate foods. According to high exposure to acrylamide, recognition of its toxic effect is ...
متن کاملOxidative Stress on Male Reproductive Toxicity
Globally Harmonized System defines Reproductive Toxicity as “an adverse effects (of chemicals) on sexual function and fertility in adult males and females, as well as developmental toxicity in the offspring.” Several toxicity assessment studies have been performed taking into account the action of toxicants on reproductive activity. Testis is the main organ of male reproductive system and sperm...
متن کاملAssessing Male Reproductive Toxicity during Drug Development
Male infertility accounts for about 50% of infertility cases [1]. Anatomic, genetic, endocrinological, environmental, behavioral and nutritional imbalances are critical causes of male infertility [2-5]. Therapeutic drugs can also adversely affect male fertility by injuring testicular cells or instigate hormonal changes that lead to decreased semen quality (Figure 1) thereby compromising the pro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Ecotoxicology and Environmental Safety
سال: 2021
ISSN: 0147-6513
DOI: 10.1016/j.ecoenv.2021.112457